Maho Tsubota Selected Research

sodium sulfide

11/2020	Essential role of Cav3.2 T-type calcium channels in butyrate-induced colonic pain and nociceptor hypersensitivity in mice.
7/2019	Genetic deletion of Cav3.2 T-type calcium channels abolishes H2S-dependent somatic and visceral pain signaling in C57BL/6 mice.
1/2016	Therapeutic potential of RQ-00311651, a novel T-type Ca2+ channel blocker, in distinct rodent models for neuropathic and visceral pain.

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Maho Tsubota Research Topics

Disease

29	Hyperalgesia 01/2021 - 01/2013
25	Pain (Aches) 02/2021 - 01/2013
9	Peripheral Nervous System Diseases (PNS Diseases) 03/2022 - 01/2016
9	Visceral Pain 01/2021 - 04/2014
8	Cystitis 01/2020 - 04/2014
7	Hypersensitivity (Allergy) 02/2021 - 01/2016
7	Inflammation (Inflammations) 01/2021 - 11/2013
5	Pancreatitis 12/2017 - 01/2013
4	Neoplasms (Cancer) 03/2022 - 01/2018
3	Interstitial Cystitis (Interstitial Cystitis, Chronic) 06/2020 - 02/2015
3	Nociceptive Pain 01/2019 - 04/2014
3	Edema (Dropsy) 01/2018 - 04/2014
2	Intractable Pain 01/2021 - 01/2018
2	Multiple Myeloma 01/2021 - 01/2019
2	Neuralgia (Stump Neuralgia) 12/2020 - 01/2018
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/2020 - 05/2020
2	Disseminated Intravascular Coagulation 01/2019 - 11/2013
2	Hyperthermia 01/2017 - 01/2017
1	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 03/2022
1	Breast Neoplasms (Breast Cancer) 05/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2021
1	Diarrhea 05/2020
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 06/2019
1	Brain Injuries (Brain Injury) 06/2019

Drug/Important Bio-Agent (IBA)

16	HMGB1 Protein (HMG1)IBA 01/2022 - 11/2013
12	ThrombomodulinIBA 05/2021 - 11/2013
9	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 04/2014
7	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2016
6	T-Type Calcium Channels (T-Type Calcium Channel)IBA 02/2021 - 01/2018
6	Thrombin FDA Link 01/2021 - 04/2014
6	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 07/2019 - 01/2014
5	Receptor for Advanced Glycation End ProductsIBA 01/2021 - 04/2014
5	Proteins (Proteins, Gene)FDA Link 12/2020 - 02/2015
5	CystathionineIBA 01/2020 - 02/2015
5	LyasesIBA 01/2020 - 02/2015
5	CeruletideIBA 12/2017 - 01/2013
4	Nuclear Proteins (Protein, Nuclear)IBA 01/2021 - 11/2013
4	Toll-Like Receptor 4IBA 01/2021 - 04/2014
4	Neutralizing AntibodiesIBA 12/2020 - 11/2013
4	Protein Isoforms (Isoforms)IBA 11/2020 - 02/2015
4	sodium bisulfide (NaHS)IBA 01/2019 - 01/2014
4	LipopolysaccharidesIBA 01/2018 - 04/2014
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2022 - 01/2018
3	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2020 - 04/2014
3	sodium sulfideIBA 11/2020 - 01/2016
3	Minocycline (Cyclops)FDA LinkGeneric 10/2018 - 01/2017
2	Adenosine Triphosphate (ATP)IBA 01/2022 - 01/2020
2	Butyrates (Butyrate)IBA 02/2021 - 11/2020
2	Dihydrotachysterol (AT 10)IBA 01/2021 - 01/2016
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2019
2	Bortezomib (Velcade)FDA Link 01/2021 - 01/2019
2	Substance PIBA 06/2020 - 01/2018
2	Capsaicin (Zostrix)FDA Link 05/2020 - 01/2014
2	Calcineurin InhibitorsIBA 05/2020 - 01/2017
2	Tacrolimus (Prograf)FDA LinkGeneric 05/2020 - 01/2017
2	Immunosuppressive Agents (Immunosuppressants)IBA 05/2020 - 01/2017
2	CalcineurinIBA 05/2020 - 01/2017
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2020 - 10/2018
2	AntioxidantsIBA 01/2020 - 02/2015
2	Calcium Channels (Calcium Channel)IBA 07/2019 - 01/2018
2	NNC 55-0396IBA 06/2019 - 02/2015
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2019 - 02/2015
2	Dacarbazine (DIC)FDA LinkGeneric 01/2019 - 11/2013
2	Clodronic Acid (Clodronate)IBA 10/2018 - 12/2017
2	prolinedithiocarbamate (PDTC)IBA 10/2018 - 01/2018
2	ethyl pyruvateIBA 10/2018 - 12/2017
2	Alanine (L-Alanine)FDA Link 01/2018 - 01/2018
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 01/2013
2	EnzymesIBA 01/2018 - 02/2015
2	ProstaglandinsIBA 01/2018 - 01/2017
2	ZincIBA 01/2018 - 02/2015
2	Analgesics (Analgesic Drugs)IBA 01/2016 - 11/2013
2	GasotransmittersIBA 02/2015 - 01/2014
1	Estrogens (Estrogen)FDA Link 05/2021
1	Dopamine D2 Receptor AntagonistsIBA 01/2021
1	sym-trinitrobenzeneIBA 01/2021
1	Pimozide (Orap)FDA Link 01/2021
1	Sulfonic AcidsIBA 01/2021
1	Antipsychotic Agents (Antipsychotics)IBA 01/2021
1	Bepridil (Vascor)FDA Link 01/2021
1	CaspasesIBA 01/2021
1	Ubiquitin-Specific ProteasesIBA 12/2020
1	PAR-2 ReceptorIBA 11/2020
1	capsazepineIBA 05/2020
1	Acrolein (Aqualin)IBA 01/2020
1	argatroban (MPQA)FDA Link 10/2019
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2019
1	Dabigatran FDA Link 10/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2019
1	Clopidogrel (Plavix)FDA Link 10/2019
1	AnticoagulantsIBA 10/2019
1	Warfarin (Coumadin)FDA LinkGeneric 10/2019
1	RivaroxabanIBA 10/2019
1	2- (4- cyclopropylphenyl)- N- (1- (5- ((2,2,2- trifluoroethyl)oxo)pyridin- 2- yl)ethyl)acetamideIBA 07/2019
1	Pharmaceutical PreparationsIBA 01/2019

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 03/2022 - 01/2016
2	Ligation 01/2018 - 01/2018
1	Therapeutics 05/2021
1	Intravesical Administration 06/2020
1	Pain Management 01/2019